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The Toxco Chemical Factory is a location featured in the Eastman and Laird's Teenage Mutant Hero Turtles Adventures series.

Reaching out to the Turtles via a link from her Turtlecom to their television set, April O'Neil tells the guys that she's in the Toxco Chemical Factory in New Jersey. She says that there is something dirty going on. She's discovered they're dumping poisonous waste into the Hudson River. April sneaked into the factory processing factory, but she was seen. She says she was followed, but managed to lose them. Unfortunately, April doesn't notice a man in a hard hat sneaking up behind her. Leonardo tries to warn her, but April is grabbed from behind and the transmission is cut-off.

In the Turtle Van, the Turtles race to the factory, which is surrounded by razor wire. The factory grounds are patrolled by guard dogs, but Donatello makes friends by offering them pizza. Using April's notepads to give one of the dogs her scent, they follow it to a warehouse. There they discover that April is in serious trouble and about to be dropped into a pool of sludge. The evil Factory Boss sends robots to attack the Turtles, but the robots are no match for the green team. The guys rescue April and later in her newscast she gives ‘certain friends’ of hers credit for putting Toxco out of business.

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