Is there a real Irma in the series?
Well according to some of the producers of the series, she may or may not return.
But if she does, let's look at the possibilities-
1.the kraang could have captured her and made a robot copy.
2 .like April, she could be a hybrid (half-human/half-kraang) and was captured by kraang who used her DNA to help them perfect the mutagen.
3.she could of escaped the kraang and is currently somewhere in dimension x.
4.the kraang could be experimenting on her.
5.the kraang could have her in stasis(like hypersleep) somewhere
6.while irma/kraang subprime infiltrated and destroyed the lair, the real Irma could have been mutated or evacuated from the city when the kraang began their invasion.
I like to think that there is a real Irma in the series and one of these possibilities is most likely but I could be wrong.