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1492 is issue 40 of the TMNT Adventures, and was published in January 1993.
The turtles, Splinter and Ninjara leave Brazil on their way home to the USA. Ending up in a storm out at the Caribbean Sea, they're transported backwards in time to 1492 ending up witnessing Christopher Columbus discovering the existence of America for the western world. Another similair storm later takes them back to their own time.