Board Thread:General Discussion/@comment-1255374-20150228233509/@comment-4682609-20150319053812

ChristopherRedfield246 wrote: Well, if this is the episode is the end of the Kraang storyline, they'll be focusing more on the Shredder storyline more, so we'll probably see more of Karai then, and maybe find out sooner what happens. I don't know. The Kraang maybe back in Dimension X, but I have a feeling we haven't seen the last of them.

As for Shredder, I doubt he'll ever find a way to cure Karai of her mutation unless he found a way to wipe her memories of the truth clean if he did.