Mrs. O'Neil (2012 TV series)

Mrs. O'Neil is the mother of April O'Neil in the 2012 TV series. She was married to Kirby O'Neil and disappeared when April was 6 years old.

History
Karai's Vendetta - April first mentions her, and Karai is distracted by the fact that April has lost her mother as well and April manages to escape.

The Kraang Conspiracy - Mrs. O'Neil appears for the first time in an old family photo and Jack Kurtzman revealed the extradimensional Kraang abducted her before April was born. The extradimensional Kraang wanted for yet unexplained reasons a suitable human host for their plans of conquest for the Earth and finally found it in Mrs. O'Neil. They kidnapped and subjected her to experiments in which her human DNA was mixed with the genetic material of the Kraang. As a result of this engagement April was born half Kraang, half human.

Buried Secrets - The turtles find April's long-lost mother frozen in a Kraang ship buried under the farmhouse, though it's not really her it's a kraang-human hybrid with Mrs. O'Neil's memories, Raphael called it "Mom Thing" as a nod to John Carpenter's The Thing.

Trivia

 * In Buried Secrets she's voiced by Renae Jacobs, who voiced in the 1987 TV series.