Board Thread:General Discussion/@comment-11016223-20130904052318/@comment-8465141-20130904212715

Technically they are related. When the turteles mutated to become anthropomorphic they needed some source of human DNA, otherwise they would just have been oversized, mutated turtles. The human DNA that allowed them to become semi-human was that of Hamato Yoshi (Splinter before he himself mutated) Therefore the turtles are 'technically related' to Splinter and thus also 'technically related' to Karai as well. Just stating the facts.